化学系

UNDERGRADUATE EDUCATION
当前位置: 首页 > 师资队伍 > 专任教师 > 化学系 > 正文

卿志和

发布日期: 2018-09-01 来源:

卿志和,男,博士,副教授,研究生导师,细胞化学湖南省重点实验室副主任。

湖南省优博,湖南省优青,长沙理工大学“湖湘学者”拔尖人才。

E-mailqingzhihe@163.com

电话:13548566090

 

从事分子水平和纳米尺度的生化分析与传感研究,得到了国家自然科学基金青年/面上项目、湖南省自然科学基金青年/优青项目、湖南省教育厅科学研究基金一般/优青项目等课题的资助。共发表SCI论文60余篇,其中以第一作者或通讯作者在Angew. Chem.Nano TodayChem. Sci.Anal. Chem.Environ. Sci. Technol.Chem. Commun.CCS Chem.Sci. China. Chem.Biosens. Bioelectron.等国内外权威期刊上发表学术论文多篇。研究成果得到了国内外同行的高度关注、肯定与参考, 总引用2700余次。申请国家发明专利5项。获得湖南省自然科学一等奖、湖南省优秀博士学位论文奖、长沙市自然科学优秀学术成果一等奖、长沙理工大学湖湘学者拔尖人才、长沙理工大学优秀教师等奖项。担任核心期刊《分析试验室》青年编委、SCI期刊《Frontiers in Chemistry》客座编辑、多部国际权威期刊审稿人、湖南省化学化工学会理事。作为研究方向带头人,建设、成立了细胞化学湖南省重点实验室,并担任副主任。担任MadeNew生物科技有限公司技术顾问,努力推进产学研合作,在生物医学、食品安全等相关领域产生社会、经济效益。

课题组欢迎化学、生物等专业的优秀本科毕业生报考!

【教育与工作经历】

[1] 2019/11-2020/11, University of Waterloo, 访问学者

[2] 2018/1-至今,长沙理工大学化学与食品工程学院,教学科研,副教授

[3] 2015/4-2017/12,长沙理工大学化学与食品工程学院,教学科研,讲师

[4] 2011/9–2014/12,湖南大学化学化工学院,分析化学,博士

[5] 2009/9–2011/7,湖南大学生物医学工程中心,生物医学工程,硕士

[6] 2005/9–2009/7,云南师范大学生命科学学院,生物科学,学士

【主讲课程】

[1] 本科生课程:《分析化学》,《分析化学实验》等

[2] 研究生课程:《化学前沿进展》,《生命分析化学》等

【近年主持或参与科研项目】

[1].   国家自然科学基金, 220740081:L型荧光放大成像机理的构建及高对比度细胞成像分析,主持。

[2].   湖南省教育厅科学研究基金, 20B026,残余农药的可视化检测探针构建及传感应用研究,主持。

[3].   湖南省自然科学基金, 2019JJ30025,基于新型核酸探针的生化分析与传感,主持。

[4].    国家自然科学基金, 21605008,基于核酸-金属纳米胶束激活式荧光成像引导的癌细胞内药物控释,主持。

[5].   湖南省自然科学基金,2016JJ3001BMVC/DNA-CuNP双光子荧光传感平台构建及生命分析应用,主持。

[6].    湖南省教育厅科学研究基金, 16C0032DNA-CuNPs/ EBMVC-B纳米复合探针的构建及其对氰化物的快速检测研究,主持。

[7].    化学生物传感与计量学国家重点实验室开放基金,2015003DNA-铜纳米材料的双光子性质研究及探针构建,主持。

[8].   湖南省水生资源食品加工工程技术研究中心开放基金,2016GCZX04BMVC/DNA-CuNP双光子荧光探针的构建及在食品质量监控中的应用,主持。

[9].   国家自然科学基金,21575018,基于DNA三链SERS传感平台构建及生命分析应用,参与(排名第二)

[10].  湖南省教育厅科学研究基金, 17A002,肝靶向近红外香豆素基荧光探针分子设计、合成及性能研究,参(排名第二)。

【近年代表性论文】

[1].   Zhihe Qing; Guoyan Luo; Shuohui Xing; Zhen Zou; Yanli Lei; Juewen Liu*; Ronghua Yang*; Pt-S Bond-Mediated Nanoflares for High-Fidelity Intracellular Applications by Avoiding Thiol Cleavage , Angewandte Chemie International Edition, 2020, 59(33): 14044-14048.SCI 1区)。

[2].   Zhihe Qing*; Jingyuan Xu; Jinlei Hu; Jing Zheng; Lei He; Zhen Zou; Sheng Yang; Weihong Tan; Ronghua Yang*; In Situ Amplification-Based Imaging of RNA in Living Cells, Angewandte Chemie International Edition, 2019, 58(34): 11574-11585. SCI 1区)

[3].   Zhihe Qing; Xiaoxiao He; Dinggeng He; Kemin Wang*; Fengzhou Xu; Taiping Qing; Xue Yang; Poly(thymine)-templated selective formation of fluorescent copper nanoparticles, Angewandte Chemie International Edition, 2013, 52(37): 9719-9722. SCI 1区)

[4].   Fengzhou Xu; Taiping Qing; Zhihe Qing*; DNA-coded metal nano-fluorophores: Preparation, properties and applications in biosensing and bioimaging, Nano Today, 2021, 36: 101021-101042. SCI 1区)

[5].   Zhihe Qing*, Yacheng Li, Younan Li, Guoyan Luo, Jinlei Hu, Zhen Zou, Yanli Lei, Juewen Liu, Ronghua Yang*. Thiol-suppressed I2-etching of AuNRs: acetylcholinesterase-mediated colorimetric detection of organophosphorus pesticides. Microchimica Acta, 2020, 187, 497-506. SCI 2区)

[6].   Zixin Jiang, Bo Feng*, Jin Xu, Taiping Qing*, Peng Zhang, Zhihe Qing*. Graphene biosensors for bacterial and viral pathogens. Biosensors and Bioelectronics, 2020, 166, 112471. SCI 1区)

[7].   Zhihe Qing*, Ailing Bai, Lifang Chen, Shuohui Xing, Zhen Zou, Yanli Lei, Junbin Li, Juewen Liu, and Ronghua Yang*. An Activatable Nano-Enzyme Reactor for Co-Enhanced Chemodynamic and Starving Therapy against Tumor Hypoxia and Antioxidant Defense System. CCS Chemistry. 2020, 2, 1217-1230.

[8].   Zhihe Qing*, Jinlei Hu, Jingyuan Xu, Zhen Zou, Yanli Lei, Taiping Qing, Ronghua Yang*. An intramolecular catalytic hairpin assembly on a DNA tetrahedron for mRNA imaging in living cells: improving reaction kinetics and signal stability. Chemical Science, 2020, 11, 1985-1990. SCI 1区)

[9].   Zhihe Qing*, Ailing Bai, Shuohui Xing, Zhen Zou, Xiaoxiao He, Kemin Wang, Ronghua Yang*. Progress in biosensor based on DNA-templated copper nanoparticles. Biosensors and Bioelectronics, 2019, 137, 96–109. SCI 1区)

[10].  Younan Li, Guoyan Luo, Zhihe Qing*, Xiaoxuan Li, Zhen Zou, and Ronghua Yang*. Colorimetric aminotriazole assay based on catalase deactivation-dependent longitudinal etching of gold nanorods. Microchimica Acta, 2019, 186, 565-571. SCI 2区)。

[11].  Zhihe Qing, Lixuan Zhu, Lina Hou, Zhen Zou, Sheng Yang, Ronghua Yang*. A dsDNA-lighted fluorophore for monitoring protein-ligand interaction through binding-mediated DNA protection. Science China Chemistry, 2018, 61, 1630-1636. SCI 1区)

[12].  Zhihe Qing, Lixuan Zhu, Xiaoxuan Li, Sheng Yang, Zhen Zou, Jingru Guo, Zhong Cao, and Ronghua Yang*. A Target-Lighted dsDNA-Indicator for High-Performance Monitoring of Mercury Pollution and Its Antagonists Screening. Environment Science & Technology, 2017, 51, 11884−11890. SCI 1区)

[13].  Lixuan Zhu, Zhihe Qing*, Lina Hou, Sheng Yang, Zhen Zou, Zhong Cao,and Ronghua Yang*. Direct Detection of Nucleic Acid with Minimizing Background and Improving Sensitivity Based on a Conformation-Discriminating Indicator. ACS Sensors 2017, 2, 1198−1204. SCI 1区)

[14].  Changhui LiuWeiju ChenZhihe Qing*Jing ZhengYue XiaoSheng YangLili WangYinhui LiRonghua Yang*In Vivo Lighted Fluorescence via Fenton Reaction: A New Approach for Imaging of Hydrogen Peroxide in Living SystemsAnalytical Chemistry, 2016, 88, 3998−4003. SCI 1区)

[15].  Le Yang, Zhihe Qing*, Changhui Liu, Qiao Tang, Jishan Li, Sheng Yang, Jing Zheng, Ronghua Yang*, and Weihong TanDirect Fluorescent Detection of Blood Potassium by Ion-Selective Formation of Intermolecular G‑Quadruplex and Ligand BindingAnalytical Chemistry, 2016, 88, 9285−9292. SCI 1区)

[16].   Zhihe Qing*Lixuan ZhuSheng YangZhong CaoXiaoxiao HeKemin WangRonghua Yang*In situ formation of fluorescent copper nanoparticles for ultrafastzero-background Cu2+ detection and its toxicides screeningBiosensors and Bioelectronics201678, 471-476. SCI 1区)

[17].   Zhihe Qing, Lina Hou, Le Yang, Lixuan Zhu, Sheng Yang, Jing Zheng, Ronghua Yang*. A Reversible Nanolamp for Instantaneous Monitoring of Cyanide Based on an Elsner-like Reaction. Analytical Chemistry, 2016, 88, 9759−9765. SCI 1区)

[18].   Zhihe Qing, Xiaoxiao He, Taiping Qing, Kemin Wang*, Hui Shi, Dinggeng He, Zhen Zou, Lvan Yan, Fengzhou Xu, Xiaosheng Ye, Zhengui Mao. Poly(thymine)-templated fluorescent copper nanoparticles for ultrasensitive label-free nuclease assay and its inhibitors screening. Analytical Chemistry, 2013, 85, 12138−12143. SCI 1区)

[19].  Zhihe Qing, Xiaoxiao He*, Jin Huang, Kemin Wang*, Zhen Zou, Taiping Qing, Zhengui Mao, Hui Shi, Dinggeng He. Target-catalyzed dynamic assembly-based pyrene excimer switching for enzyme-free nucleic acid amplified detection. Analytical Chemistry, 2014, 86, 4934−4939. SCI 1区)

[20].  Zhihe Qing, Zhengui Mao*, Taiping Qing, Xiaoxiao He, Zhen Zou, Dinggeng He, Hui Shi, Jin Huang, Jianbo Liu, and Kemin Wang*. Visual and portable strategy for copper (II) detection based on a striplike poly(thymine)-caged and microwell-printed hydrogel. Analytical Chemistry, 2014, 86, 11263−11268. SCI 1区)

[21].   Zhihe Qing, Taiping Qing, Zhengui Mao, Xiaoxiao He*, Kemin Wang*, Zhen Zou, Hui Shi and Dinggeng He. dsDNA-specific fluorescent copper nanoparticles as a “green” nano-dye for polymerization-mediated biochemical analysis. Chemical Communications, 2014, 50, 12746–12748. SCI 1区)

[22].    Zhengui Mao#, Zhihe Qing#, Taiping Qing, Fengzhou Xu, Li Wen, Xiaoxiao He*, Dinggeng He, Hui Shi, and Kemin Wang*. Poly(thymine)-Templated Copper Nanoparticles as a Fluorescent Indicator for Hydrogen Peroxide and Oxidase-Based Biosensing. Analytical Chemistry2015, 85, 7454-7460.SCI 1区)

 

 

    友情链接

    LINKS