姓 名：周怡波
职 称：副教授
导师资格：硕士生导师
邮 箱：yibozhou@163.com
研究方向：有机荧光分子、聚合物材料制备及生物成像应用
简介：周怡波，理学博士，副教授，硕士生导师，长沙市杰青，湖南省青年骨干教师，长沙理工大学“湖湘学者”青年英才，细胞化学湖南省重点实验室副主任。主持承担国家自然科学基金、湖南省自然科学基金项目等课题8项。在J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Chem. Sci.、 Anal. Chem.等期刊发表论文多篇。获得湖南省自然科学二等奖、湖南省化学化工学会第十八届青年化学化工奖等荣誉。
近五年代表性论文：
(1) Yibo Zhou, Pin Shang, Huiqiu Shi, Jun Zhang, Fan Li, Zhihe Qing*, and Tony D. James*. Asymmetric Sulfydryl-Substituted Squaraine Fluorophores for Sustained SIM Imaging in Live Cells. J. Am. Chem. Soc., 2026, org/10.1021/jacs.6c06633.
(2) Yibo Zhou, Yuping Wang, Aoshuang Xu, Qiuhong Mo, Xiaowen Liu, Min Liu, Xiaohan Zhang, Juewen Liu, Zhihe Qing*. Physically Masked Nanoflares for Accurate Biological Applications by Blocking Nucleases. Angew. Chem. Int. Ed., 2026, 65, e13763.
(3) Yibo Zhou, Zhengxuan Gu, Changhui Liu, Sheng Yang*, Xiaofei Ma, Qiaoshu Chen, Yanli Lei, Ke Quan, Juewen Liu, Zhihe Qing*,Ronghua Yang*. A Polymeric Nanobeacon for Revealing Hydrogen Polysulfides Fluctuation during Fertilization and Embryonic Development. Angew. Chem. Int. Ed., 2022, 61, e202114504.
(4) Yibo Zhou*, Pin Shang, Jun Zhang, Zhihe Qing*, and Tony D. James*. Hydrogen selenide in biological systems: from synthetic donors to fluorescent probes. Chem. Sci., 2026, 10.1039/d6sc05851e.
(5) Yibo Zhou, Aoshuang Xu, Ke Quan, Yanli Lei, Xiaohan Zhang, Juewen Liu, and Zhihe Qing*. High-Fidelity Nanoflares: Design Strategies, Response Mechanisms, and Biomedical Applications. Chem. Sci., 2026, 10.1039/d6sc04006c.
(6) Xiaowen Liu, Shuanghong Sun, Xinchao Xia, Huiqiu Shi, Le Yang, Zenghui Mao, Xianjin Xiao, Yibo Zhou*, Zhihe Qing*. Uncovering the Fluctuation of Peroxynitrite during Early Embryonic Development Using an Integrative Nanobeacon. Anal. Chem., 2025, 97, 6192-6200.
(7) Le Yang, Xinchao Xia, Fan Li, Qiuhong Mo, Pin Shang, Junbin Li, Yi Li, Yibo Zhou*, Zhihe Qing*. Fluorescent visualization of endoplasmic reticulum stress induced by microplastic pollution via surge of intracellular reactive oxygen species. Anal. Chim. Acta., 2025, 1380, 344777.
(8) Yibo Zhou*, Jun Zhang, Shuanghong Sun, Weiju Chen, Yuping Wang, Huiqiu Shi, Ronghua Yang*, Zhihe Qing*. Amplified biosensor powered by endogenous molecules for intracellular fluorescence imaging. Anal. Chem., 2024, 96, 20, 8078-8090.
(9) Yibo Zhou*, Huiqiu Shi, Xinchao Xia, Sheng Yang*, Junbin Li, Zhihe Qing, Jing Zheng, and Ronghua Yang. Integration of Hybridization Chain Reaction and Protein-Binding Amplification for Long-Term Imaging of Intracellular mRNA: Avoiding Signal Fluctuation. Anal. Chem., 2024, 96, 11061-11067.
(10) Ni Zeng, Xiuhong Guan, Xiaowen Liu, Huiqiu Shi, Nan Li, Ruimeng Yang, Yibo Zhou*. Fibroblast activation protein-sensitive polymeric nanobeacon for early diagnosis of renal fibrosis. Biosens. Bioelectron., 2024, 253, 116144.
(11) Junbin Li, Na Wang, Mengyi Xiong*, Min Dai, Cheng Xie, Qianqian Wang, Ke Quan, Yibo Zhou*, Zhihe Qing*. A Reaction-Based Ratiometric Bioluminescent Platform for Point-of-Care and Quantitative Detection Using a Smartphone, Anal. Chem., 2023, 95, 18, 7142-7149.
(12) Yibo Zhou, Xiaofei Ma, Shan Hu, Sheng Yang, Jingru Guo, Junbin Li, Yue-Fei Zhang, Juewen Liu, Zhihe Qing*, Ronghua Yang*. Rigidity-Dependent Emission: Inspired Selection of an ATP-Specific Polyvalent Hydrogen Binding-Lighted Fluorophore for Intracellular Amplified Imaging, Anal. Chem., 2023, 95, 21, 8318-8324.
(13) Taoyun Wang, Xu Huang, Sheng Yang, Shan Hu, Xianglan Zheng, Guojiang Mao, Yi Li*, Yibo Zhou*. Monitoring H2S fluctuation during autophagic fusion of lysosomes and mitochondria using a lysosome-targeting fluorogenic probe, Anal. Chim. Acta., 2023, 1265, 341356.
(14) Huihong Liu, Xianqing Zeng, Honghui Yin, Jing Chen, Wenzhi Xie, Guoqiang Zhou, Guojiang Mao, Yibo Zhou*, Sheng Yang*. A pH-switchable azo-based fluorescence reporter for lysosome-confined visualization of hypoxia status. Sens. Actuators B Chem., 2023, 381, 133431.
(15) Qiuhong Mo, Jun Zhang, Pin Shang, Yibo Zhou*, Zhihe Qing. Research Progress on Delivery and Detection of Hydrogen Selenide in Vivo. Acta Chim. Sinica, 2026, 84, 448-458.
(16) Yibo Zhou*, Shan Hu, Hongwen Liu, Xinyue Xiao, Weiju Chen, Sheng Yang, Huiqiu Shi, Zhenxuan Gu, Junbin Li, Ronghua Yang*, Zhihe Qing*. Activity-Independent Enzyme-Powered Amplification for Improving Signal Stability and Fidelity in Biosensing. Chemical & Biomedical Imaging, 2024, 2, 4, 304-312.
