性别：男

最高学历：博士

系室：化学系

邮箱：yibozhou@163.com

教育背景：

2013.09 – 2017.12        湖南大学化学化工学院         分析化学/博士

2009.09 – 2012.06        湖南大学化学化工学院         物理化学/硕士

2005.09 – 2009.06        吉首大学化学化工学院         化学/学士

科研情况：

◉科研项目：

1、国家自然科学基金面上项目，22674020，2027/01-2030/12，在研，主持。

2、国家自然科学基金青年项目C类，21804012，2019/01-2021/12，已结题，主持。

3、长沙市杰出青年科技人才培养计划，kq2506009，2025/01-2027/12，在研，主持。

4、湖南省自然科学基金面上项目，2025JJ50061，2025/01-2027/12，在研，主持。

5、湖南省教育厅优秀青年基金项目，23B0308，2023/10-2025/10，已结题，主持。

6、湖南省自然科学基金青年基金项目，2019JJ50634，2019/01-2021/12，已结题，主持。

7、长沙市自然科学基金，kq2208216，2023/01-2024/12，已结题，主持。

◉科研论文(近5年)：

(1)Yibo Zhou, Pin Shang, Huiqiu Shi, Jun Zhang, Fan Li, Zhihe Qing^*, and Tony D. James^*. Asymmetric Sulfydryl-Substituted Squaraine Fluorophores for Sustained SIM Imaging in Live Cells. J. Am. Chem. Soc., 2026, org/10.1021/jacs.6c06633. (A1)

(2)Yibo Zhou, Yuping Wang, Aoshuang Xu, Qiuhong Mo, Xiaowen Liu, Min Liu, Xiaohan Zhang, Juewen Liu, Zhihe Qing^*. Physically Masked Nanoflares for Accurate Biological Applications by Blocking Nucleases. Angew. Chem. Int. Ed., 2026, 65, e13763. (A1)

(3)Yibo Zhou, Zhengxuan Gu, Changhui Liu, Sheng Yang^*, Xiaofei Ma, Qiaoshu Chen, Yanli Lei, Ke Quan, Juewen Liu, Zhihe Qing^*, Ronghua Yang^*. A Polymeric Nanobeacon for Revealing Hydrogen Polysulfides Fluctuation during Fertilization and Embryonic Development. Angew. Chem. Int. Ed., 2022, 61, e202114504. (A1)

(4)Yibo Zhou*, Pin Shang, Jun Zhang, Zhihe Qing^*, and Tony D. James^*. Hydrogen selenide in biological systems: from synthetic donors to fluorescent probes. Chem. Sci., 2026, 10.1039/d6sc05851e. (A1)

(5)Yibo Zhou, Aoshuang Xu, Ke Quan, Yanli Lei, Xiaohan Zhang, Juewen Liu, and Zhihe Qing^*. High-Fidelity Nanoflares: Design Strategies, Response Mechanisms, and Biomedical Applications. Chem. Sci., 2026, 10.1039/d6sc04006c. (A1)

(6)Xiaowen Liu, Shuanghong Sun, Xinchao Xia, Huiqiu Shi, Le Yang, Zenghui Mao, Xianjin Xiao, Yibo Zhou*, Zhihe Qing^*. Uncovering the Fluctuation of Peroxynitrite during Early Embryonic Development Using an Integrative Nanobeacon. Anal. Chem., 2025, 97, 6192-6200. (A1)

(7)Le Yang, Xinchao Xia, Fan Li, Qiuhong Mo, Pin Shang, Junbin Li, Yi Li, Yibo Zhou*, Zhihe Qing^*. Fluorescent visualization of endoplasmic reticulum stress induced by microplastic pollution via surge of intracellular reactive oxygen species. Anal. Chim. Acta., 2025, 1380, 344777. (A1)

(8)Yibo Zhou*, Jun Zhang, Shuanghong Sun, Weiju Chen, Yuping Wang, Huiqiu Shi, Ronghua Yang^*, Zhihe Qing^*. Amplified biosensor powered by endogenous molecules for intracellular fluorescence imaging. Anal. Chem., 2024, 96, 20, 8078-8090. (A1)

(9)Yibo Zhou*, Huiqiu Shi, Xinchao Xia, Sheng Yang^*, Junbin Li, Zhihe Qing, Jing Zheng, and Ronghua Yang. Integration of Hybridization Chain Reaction and Protein-Binding Amplification for Long-Term Imaging of Intracellular mRNA: Avoiding Signal Fluctuation. Anal. Chem., 2024, 96, 11061-11067. (A1)

(10)Ni Zeng, Xiuhong Guan, Xiaowen Liu, Huiqiu Shi, Nan Li, Ruimeng Yang, Yibo Zhou*. Fibroblast activation protein-sensitive polymeric nanobeacon for early diagnosis of renal fibrosis. Biosens. Bioelectron., 2024, 253, 116144. (A1)

(11)Junbin Li, Na Wang, Mengyi Xiong^*, Min Dai, Cheng Xie, Qianqian Wang, Ke Quan, Yibo Zhou*, Zhihe Qing^*. A Reaction-Based Ratiometric Bioluminescent Platform for Point-of-Care and Quantitative Detection Using a Smartphone, Anal. Chem., 2023, 95, 18, 7142-7149. (A1)

(12)Yibo Zhou, Xiaofei Ma, Shan Hu, Sheng Yang, Jingru Guo, Junbin Li, Yue-Fei Zhang, Juewen Liu, Zhihe Qing^*, Ronghua Yang^*. Rigidity-Dependent Emission: Inspired Selection of an ATP-Specific Polyvalent Hydrogen Binding-Lighted Fluorophore for Intracellular Amplified Imaging, Anal. Chem., 2023, 95, 21, 8318-8324. (A1)

(13)Taoyun Wang, Xu Huang, Sheng Yang, Shan Hu, Xianglan Zheng, Guojiang Mao, Yi Li^*, Yibo Zhou*. Monitoring H₂S fluctuation during autophagic fusion of lysosomes and mitochondria using a lysosome-targeting fluorogenic probe, Anal. Chim. Acta., 2023, 1265, 341356. (A1)

(14)Huihong Liu, Xianqing Zeng, Honghui Yin, Jing Chen, Wenzhi Xie, Guoqiang Zhou, Guojiang Mao, Yibo Zhou*, Sheng Yang^*. A pH-switchable azo-based fluorescence reporter for lysosome-confined visualization of hypoxia status. Sens. Actuators B Chem., 2023, 381, 133431. (A1)

(15)Qiuhong Mo, Jun Zhang, Pin Shang, Yibo Zhou*, Zhihe Qing. Research Progress on Delivery and Detection of Hydrogen Selenide in Vivo. Acta Chim. Sinica, 2026, 84, 448-458. (A2)

(16)Yibo Zhou*, Shan Hu, Hongwen Liu, Xinyue Xiao, Weiju Chen, Sheng Yang, Huiqiu Shi, Zhenxuan Gu, Junbin Li, Ronghua Yang^*, Zhihe Qing^*. Activity-Independent Enzyme-Powered Amplification for Improving Signal Stability and Fidelity in Biosensing. Chemical & Biomedical Imaging, 2024, 2, 4, 304-312. (A2)

◉科研奖励：

1. 湖南省自然科学二等奖

2. 长沙市杰出青年培养计划

3. 湖南省普通高校青年骨干教师

4. 长沙理工大学“湖湘学者”青年英才

5. 湖南省化学化工学会第十八届青年化学化工奖

6. 湖南省优秀硕士论文指导教师

◉ 发明专利：

1. 周怡波，尹柯仪，杨荣华。一种能长时间成像FAP的生物发光探针及其应用, 2022-9-13, 中国, ZL2020 1 0860240.4

2. 周怡波，胡山，杨荣华。一种响应ATP的荧光染料及其制备方法和应用, 2024-1-3, 中国, ZL 2022 1 1374678.7

3. 周怡波，胡山，肖新月，卿志和。一种响应羧酸酯酶荧光染料及其制备方法及应用，2023-12-15, 中国, ZL 2023 1 1730996.7

教学情况：

主讲本科生《仪器分析》、《分析化学实验》、研究生《分子光谱学》《化学生物学》等课程。

◉教改项目及教改论文：

1、学位与研究生教学改革研究项目，基于大型科研仪器的专业学位研究生实践课程改革，2023/12-2025/12，在研，主持

2、“激光扫描共聚焦显微镜在本科实验教学应用初探“，山东化工：2021，50，212.

3、“理工科院校分析测试中心发展及思考-以长沙理工大学为例“，广东化工，2021，48，273.

研究生招生:

本课题组开展生化传感相关领域基础和应用研究，优秀毕业生可推荐到知名大学或研究所攻读博士学位。欢迎具有生物、化学、化工等背景的有志同学报考研究生！